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Quick Bisquick Upside-Down Pizza

Quick Bisquick Upside-Down Pizza

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Submitted by lauramimi

This Quick Upside-Down Pizza is a delightful twist on traditional pizza, transforming it into a hearty casserole that’s easy to prepare and packed with flavor. Layers of seasoned ground beef, onions, mozzarella cheese, and tangy spaghetti sauce are topped with a fluffy biscuit mix batter, creating a dish that’s both comforting and satisfying. Perfect for busy weeknights or casual gatherings, this recipe is a crowd-pleaser that serves 6–8.

YIELD

6 servings

PREP

15 min

COOK

30 min

READY

45 min

Quick Upside-Down Pizza

Chef Tips

  • No Bisquick? No problem!: Easy Homemade Bisquick Biscuit Mix
  • Drain Beef Thoroughly: Excess fat can make the casserole greasy. Use lean ground beef (85% or higher) and drain well after cooking.
  • Even Layering: Spread each layer evenly to ensure consistent flavor and texture in every bite.
  • Check Oven Temperature: Ovens vary, so use an oven thermometer if possible. If the topping browns too quickly, cover loosely with foil.
  • Make Ahead: Assemble the casserole (without baking) up to 24 hours in advance, cover, and refrigerate. Add 5–10 minutes to the baking time if cooking from cold.
  • Serving Suggestion: Pair with a simple green salad or garlic bread for a complete meal.

Optional Variations

  • Vegetarian: Replace ground beef with plant-based crumbles or a mix of sautéed mushrooms, bell peppers, and zucchini.
  • Spicy Kick: Add ½ teaspoon red pepper flakes to the beef or use a spicy spaghetti sauce.
  • Meat Lovers: Mix in ½ cup cooked Italian sausage or pepperoni slices with the beef.
  • Veggie Boost: Stir ½ cup chopped bell peppers or sliced olives into the spaghetti sauce before layering.
  • Cheese Swap: Substitute mozzarella with a blend of cheddar and Monterey Jack for a different flavor profile.

Potential Pitfalls and How to Avoid Them

  • Soggy Topping: Ensure the biscuit batter is evenly spread and not too thin. Avoid opening the oven door frequently to maintain consistent heat.
  • Uneven Cooking: Use a 9×13-inch dish for proper layering and baking. Smaller dishes may require longer cooking times and lead to uneven results.
  • Overly Salty Dish: Taste your spaghetti sauce beforehand, as some brands are saltier. Adjust the added salt if needed.

Ingredients

1 453.6
POUND G BEEF
ground
454.0
1 1
JAR JAR SPAGHETTI SAUCE
large jar *
8 231.2
OUNCES ML/G MOZZARELLA CHEESE
shredded
224.0
½ 118
CUP ML ONIONS
80.0
1 5
TEASPOON ML GARLIC SALT
2.0
¼ 1.3
TEASPOON ML SALT
1.52
¼ 1.3
TEASPOON ML BLACK PEPPER
0.5
2 2
LARGE LARGE EGGS
100.0
1 237
CUP ML MILK
244.0

Directions

  1. Preheat Oven: Preheat your oven to 375°F (190°C) to ensure even cooking.
  2. Cook Beef: In a large skillet over medium heat, cook the ground beef, breaking it apart with a spatula, until fully browned and no pink remains (about 5–7 minutes). Drain excess fat to prevent a greasy casserole. Set aside.
  3. Prepare Batter: In a medium mixing bowl, whisk together the biscuit baking mix, eggs, and milk until smooth (about 1–2 minutes). The batter should be pourable but slightly thick, similar to pancake batter.
  4. Layer Ingredients: In a 9×13-inch casserole dish, layer the ingredients in the following order:
    • Spread the cooked ground beef evenly across the bottom.
    • Sprinkle the chopped onion over the beef.
    • Season with garlic salt, kosher salt, and black pepper.
    • Evenly distribute the shredded mozzarella cheese.
    • Pour the spaghetti sauce over the cheese, spreading it gently with a spatula to cover.
    • Carefully pour the biscuit batter over the sauce, ensuring it covers the entire surface.
    • Add Topping: Sprinkle the grated Parmesan cheese evenly over the batter for a golden, flavorful crust.
  5. Bake: Place the casserole dish in the preheated oven and bake for 25–30 minutes, or until the biscuit topping is golden brown and a toothpick inserted in the center comes out clean. Check at 25 minutes to avoid overcooking.
  6. Serve: Let the casserole rest for 5 minutes before serving to allow the layers to set. Scoop portions onto plates, ensuring each serving includes all layers. Serve warm.
* not incl. in nutrient facts Arrow up button

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Nutrition Facts

Serving Size 184g (6.5 oz)
Amount per Serving
Calories 601 54% from fat
 % Daily Value *
Total Fat 36g 56%
Saturated Fat 16g 79%
Trans Fat 0g
Cholesterol 244mg 81%
Sodium 645mg 27%
Total Carbohydrate 6g 6%
Dietary Fiber 2g 9%
Sugars g
Protein 101g
Vitamin A 18% Vitamin C 15%
Calcium 56% Iron 23%
* based on a 2,000 calorie diet How is this calculated?
Trans-fat Free
 
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